The 2-Minute Rule for Promethazine codeine syrup
The 2-Minute Rule for Promethazine codeine syrup
Blog Article
It can be difficult to decide what constitutes a typical toxic or lethal dose. Having said that, the lethal oral dose of codeine in an Grownup is noted for being inside the choice of 0.
Promethazine administered to your Expecting girl within just two months of supply could inhibit platelet aggregation while in the newborn.
There is a problem with facts submitted for this ask for. Critique/update the information highlighted underneath and resubmit the form.
Choose this medication exactly as prescribed to decrease the potential risk of dependancy. Check with your health practitioner or pharmacist For additional details.
Dextromethorphan is on the market in both equally prescription and nonprescription products. Test the labels of your drugs to be sure you are certainly not using multiple product or service made up of dextromethorphan.
Remember that this medication has been prescribed since your health care provider has judged which the reward to you personally is larger than the risk of Unwanted side effects. Lots of people using this medication don't have really serious Uncomfortable side effects.
Discontinuation of the concomitantly utilized cytochrome P450 2D6 inhibitor may perhaps end in a lower in codeine plasma concentration and a rise in Lively metabolite morphine plasma concentration which could improve or prolong adverse reactions and should induce potentially deadly respiratory melancholy.
The effects of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are elaborate, requiring cautious consideration of the results within the mother or father drug, codeine, plus the active metabolite, morphine.
Warning people that some folks have a variation in the liver enzyme and change codeine into morphine more fast and totally than Other individuals. These persons are extremely-swift metabolizers and are more likely to have bigger-than-normal levels of morphine within their blood just after getting codeine which may result in overdose signs which include Extraordinary sleepiness, confusion, or shallow respiratory. In most cases, it really is unknown if another person is an ultra-swift codeine metabolizer.
It's not a complete listing of doable side effects. When you see other Uncomfortable side effects not detailed over, Make contact with your physician or pharmacist.
g., amiodarone, quinidine) might result in a rise in codeine plasma concentrations in addition to a lower in Lively metabolite morphine plasma concentration which could bring about an analgesic efficacy reduction or signs of opioid withdrawal.
To scale back the chance of dizziness and lightheadedness, stand Promethazine codeine syrup up slowly when soaring from the sitting down or lying situation.
Sedating prescription drugs could bring about confusion and more than-sedation within the aged; aged clients generally need to be begun on small doses of promethazine with codeine syrup and observed intently.
Concomitant administration of promethazine solutions with other respiratory depressants has an association with respiratory depression, and at times Dying, in pediatric people.